A systematic methodology to assess the identity of plants in historical texts: A case study based on the Byzantine pharmacy text John the Physician's Therapeutics.

ETHNOPHARMACOLOGICAL RELEVANCE: In recent decades, the study of historical texts has attracted research interest, particularly in ethnopharmacology. All studies of the materia medica cited in ancient and medieval texts share a concern, however, as to the reliability of modern identifications of these substances. Previous studies of European or Mediterranean texts relied mostly on authoritative dictionaries or glossaries providing botanical identities for the historical plant names in question. Several identities they suggest, however, are questionable and real possibility of error exists. AIM OF THE STUDY: This study aims to develop and document a novel and interdisciplinary methodology providing more objective assessment of the identity of the plants (and minerals) described in these resources. MATERIALS AND METHODS: We developed an iterative experimental approach, using the 13th century Byzantine recipe text John the Physician's Therapeutics in its Commentary version (JC) as a case study. The methodology has six stages and relies on comparative analyses including statistical evaluation of botanical descriptions and information about medicinal uses drawn from both historical and modern sources. Stages 1-4 create the dataset, stage 5 derives the primary outcomes to be reviewed by experts in stage 6. RESULTS: Using Disocorides' De Materia Medica (DMM) (1st century CE) as the culturally related reference text for the botanical descriptions of the plants cited in JC, allowed us to link the 194 plants used medicinally in JC with 252 plants cited in DMM. Our test sample for subsequent analyses consisted of the 50 JC plant names (corresponding to 61 DMM plants) for which DMM holds rich morphological information, and the 130 candidate species which have been suggested in the literature as potential botanical identities of those 50 JC plant names. Statistical evaluation of the comparative analyses revealed that in the majority of the cases, our method detected the candidate species having a higher likelihood of being the correct attribution from among the pool of suggested candidates. Final assessment and revision provided a list of the challenges associated with applying our methodology more widely and recommendations on how to address these issues. CONCLUSIONS: We offer this multidisciplinary approach to more evidence-based assessment of the identity of plants in historical texts providing a measure of confidence for each suggested identity. Despite the experimental nature of our methodology and its limitations, its application allowed us to draw conclusions about the validity of suggested candidate plants as well as to distinguish between alternative candidates of the same historical plant name. Fully documenting the methodology facilitates its application to historical texts of any kind of cultural or linguistic background.

A comprehensive review on Saraca asoca (Fabaceae) - Historical perspective, traditional uses, biological activities, and conservation.

ETHNOPHARMACOLOGICAL RELEVANCE: Saraca asoca (Roxb.)W.J.de Wilde, (Fabaceae) is a plant of significant medicinal value in traditional Indian medicine, with a long history of use in the treatment of gynaecological disorders and other ailments, and is held in high esteem. This plant has long existed in Indian tradition and is revered as sacred. AIM OF THE STUDY: This work aimed to explore the taxonomic revision of Saraca asoca from ancient times to the present and to evaluate the ethnobotanical, phytochemical and pharmacological information associated with traditional use and develop a roadmap for conservative strategies of species. MATERIALS AND METHODS: The study draws on a comprehensive range of herbal, traditional, ethnobotanical, and ethnopharmacological information, including ancient Ayurvedic textbooks and various databases, using a single keyword or a combination of multiple keywords. RESULTS: This review establishes a roadmap for understanding the traditional history of medicinal plants, particularly Saraca, and highlights the transfer of traditional knowledge from pharmacopoeias, materia medica, and classical textbooks over many centuries. The study also emphasises the importance of conservation strategies to protect Saraca as a valuable resource for healthcare and suggests that more research is needed to systematically evaluate its phytochemical, pharmacological, and clinical properties, as well as to develop safety, pharmacology, and toxicology reports for traditional formulations. CONCLUSIONS: In light of this study, S. asoca could be considered an important source of potential herbal drugs. The review concludes with a call for further research and conservation efforts to protect Saraca and other traditional medicinal plants for the benefit of current and future generations.

Female naturalists and the patterns of suppression of women scientists in history: the example of Maria Sibylla Merian and her contributions about useful plants.

BACKGROUND: This work reunites many women naturalists who registered knowledge about native flora in scientific expeditions around the globe between the seventeenth and nineteenth centuries. Since male naturalists are more recognized in this period of time, we aimed to list female naturalists that published plant descriptions and observations, focusing on the work of Maria Sibylla Merian and to analyze her trajectory as an example to discuss the patterns of the suppression of women scientists. A second aim was to inventory the useful plants described in Maria Sibylla's Metamorphosis Insectorum Surinamensium and find pharmacological evidence about the traditional uses described for those plants cited as medicinal and toxic. METHODS: A survey of female naturalists was carried out by searching information in Pubmed, Scielo, Google Scholar and Virtual Health Library. Once Maria Sibylla published her book Metamorphosis Insectorum Surinamensium by her own, without male co-authors, and also this book is one of the only to have text and illustrations altogether and there are reports indicating information on useful plants in this work, she and her book were chosen as subject of this research. All the information was tabulated by dividing the plants into food, medicinal, toxic, aromatic or other uses. Finally, with the combinations of the scientific name of medicinal and toxic plants with information about their popular uses, a search was carried out in databases in order to indicate current pharmacological studies that reported evidences about the traditional uses described. RESULTS: We found 28 women naturalists who participated in scientific expeditions or trips, or in a curiosity cabinet, or who were collectors of Natural History between the seventeenth and nineteenth centuries. All these women illustrated botanical species and/or recorded their everyday or medicinal use or reported their observations in the form of a published work, letters or diaries. Also, the trajectory of Maria Sibylla Merian revealed that her scientific relevance has been neglected from the eighteenth century by mechanisms of suppression, most of the time by male depreciation, which can be seen as a pattern for suppression of women in science. However, Maria Sibyllas' contributions have been valued again in the twenty-first century. In Maria Sibylla's work, 54 plants were identified, 26 of them used for food, 4 of them aromatic, 8 medicinal, 4 toxic and 9 other uses. CONCLUSION: This study evidences that there are female naturalists whose work could be an important source for ethnopharmacological studies. Researching about women scientists, talking about them and highlighting the gender bias present in the scientific academy about the way the history of science is told is essential for the construction of a more diverse and richer scientific academy. The traditional use of 7 of 8 medicinal plants and 3 of 4 toxic plants reported was correlated with pharmacological studies, highlighting the importance of this historical record and its potential to direct strategic research in traditional medicine.

Five centuries of Cirsium ehrenbergii Sch. Bip. (Asteraceae) in Mexico, from Huitzquilitl to Cardo Santo: History, ethnomedicine, pharmacology and chemistry.

ETHNOPHARMACOLOGICAL RELEVANCE: Several medicinal plants, including the endemic herb Cirsum ehrenbergii (Asteraceae), have been documented in manuscripts, medical and botanical books written in Mexico since the XVI century until the present. This unique circumstance is a real window in the time that allows to investigate historical and contemporary ethnopharmacological knowledge. AIM OF THE STUDY: To examine the persistence, disappearance, and transformation of ethnomedicinal knowledge of C. ehrenbergii along time. Also, to investigate the chemistry and pharmacology of this species in relation to its historical and present day main ethnomedical applications related to Central Nervous System and inflammation. MATERIALS AND METHODS: A thorough review was performed of written sources of medicinal plants from XVI and onwards. For the pharmacological studies, the organic extracts were tested in mice models to assess its antidepressant and anti-inflammatory properties. The active extracts were studied chemically. The isolated compounds were identified by 1H, 13C NMR, or characterized by GC-MS. RESULTS: Cirsum ehrenbergii was illustrated for the first time (1552) in the Libellus de Medicinalibus Indorum Herbis (Booklet of Medicinal Plants of the Indians) and named in the Nahuatl native language as huitzquilitl (edible thistle). It was there recommended as nigris sanguinis remedium (remedy for black blood), and for the treatment of illnesses with an inflammatory component. Nigris sanguinis was well known in the European medicine of that time and currently it has been interpreted as "depression". At the present time, peasants and native population in Mexico mainly name C. ehrenbergii in Spanish as cardo Santo (holy thistle). Its original Nahuatl name has been almost forgotten. However, these communities use this species, among other maladies, to heal "nervios" (anxiety and/or depression) and for anti-inflammatory purposes. These ailments and treatments resemble those recorded in the Libellus and in several medicinal plant books along centuries. The ethanol extract of C. ehrenbergii roots showed antidepressant-like activity in mice administered at 300 mg/kg, as indicated by the forced swim test (FST). The glycosylated flavonoid linarin was identified as antidepressant principle and was active at the doses of 30 and 60 mg/kg in the FST. Regarding to anti-inflammatory activity, the most active was the methylene chloride extract of the aerial parts, which contains taraxasterol, pseudotaraxasterol, ß-sitosterol and stigmasterol. CONCLUSIONS: Cirsium ehrenbergii extracts possess antidepressant-like (roots, EtOH) and anti-inflammatory (aerial parts, CH2Cl2) properties, containing active compounds. Our results sustain historical and present day ethnomedical applications of this species documented along five centuries.

[The origins and development of traditional medicine: an ideological issue]. / Orígenes y desarrollo de la medicina tradicional: una cuestión ideológica.

Most analysts identify three main foundations of the development of traditional Mexican medicine between the 15th and 18th centuries (pre-Hispanic, Hispanic, and African), as well as a number of complementary sources incorporated over the course of the 18th and 19th centuries. However, a significant proportion of leading specialists consider pre-Hispanic medicine to be the primary basis of traditional medicine, downplaying Hispanic influence and disregarding African influence. Furthermore, they either ignore or give only cursory treatment to the role of biomedicine in the present-day medicalization of traditional medicine. Although this trend can be traced back to the 1930s and 1940s, it intensified from the 1970s onward and peaked around the time of the Fifth Centennial in 1992, transforming the question of the origins and development of traditional medicine into a largely ideological issue.

La mayoría de los analistas reconocen tres fuentes básicas en el desarrollo de la medicina tradicional mexicana entre los siglos XV y XVIII (prehispánico, hispánico y afro), así como toda una serie de fuentes complementarias que se fueron incluyendo sobre todo entre los siglos XVIII y XXI. No obstante, gran parte de los principales especialistas consideran que el núcleo de la medicina tradicional es la medicina prehispánica, secundarizando lo hispánico y excluyendo lo afro. Incluso no reconocen o señalan superficialmente el papel de la biomedicina en la medicalización actual de la medicina tradicional. Si bien esta tendencia se observa desde las décadas de 1930 y 1940, se profundiza a partir de la década de 1970, para eclosionar en torno al Quinto Centenario de 1992, convirtiendo la cuestión de los orígenes y el desarrollo de la medicina tradicional en una cuestión básicamente ideológica.

Synchronic and Diachronic Factors Influencing Medieval Arabic Medical Practice: A Study of Ophthalmological Fragments Found in the Cairo Genizah.

This article addresses the practical aspect of medieval Arabic medicine by examining ophthalmological fragments of the Cairo Genizah, written between the tenth and thirteenth centuries. This article deals with two issues: (1) the logic behind the actual preparation of compound medicines and (2) the logic behind the entire treatment process. The first issue is examined by investigating recipes of eye medicines for leucoma (bayad) recorded in genizah notebooks. By examining the four primary qualities of each ingredient, I clarify how the actual prescription of compound medicines has been grounded in the four-quality theory. The second issue is examined from a reading of two genizah letters. These letters suggest that diagnostic theory actually provided the framework for the analysis of the symptoms. The diagnoses determined medieval ophthalmologists' selection of eye medicines and their method of application.

Las prácticas tradicionales del cuidado indígena mesoamericano en la historiografía de las órdenes religiosas españolas del S. XVI / The traditional practices of Mesoamerican indigenous care in the historiography of the Spanish religious orders of the S. XVI

Escribir la historia de las prácticas y acciones sobre el cuidado de la salud es examinar el problema de conceptualización en enfermería, así como, interpretar y distinguir las acciones de cuidado conscientes e inconscientes, ritualizadas, espontáneos, o como resultado del proceso de aculturación en el encuentro de dos o más culturas. Los pueblos mesoamericanos crearon un complejo ideológico simbolizado por divinidades con el que dotaron su cosmovisión, la idea del equilibrio interno con el medio externo, todo era sagrado, por lo tanto, deberían las personas propiciar el equilibrio con su entorno para beneficiar la salud (AU)

Medicina tradicional mexicana como alternativas de tratamiento desde la conquista (1552) hasta el México actual. Una visión de enfermería / Traditional Mexican Medicine as treatment alternatives, from the conquest (1552) to present-day Mexico. A vision of nursing

Analizar históricamente la medicina tradicional mexicana como alternativa de tratamiento desde la conquista (1552) hasta el México actual [Fragmento de texto] (AU)

Ca' Granda, Hortus simplicium: Restoring an Ancient Medicinal Garden of XV-XIX Century in Milan (Italy).

This work is based on the study of 150 majolica vases dated back to the mid XVII century that once preserved medicinal remedies prepared in the ancient Pharmacy annexed to the Ospedale Maggiore Ca' Granda in Milan (Lombardy, Italy). The Hortus simplicium was created in 1641 as a source of plant-based ingredients for those remedies. The main objective of the present work is to lay the knowledge base for the restoration of the ancient Garden for educational and informative purposes. Therefore, the following complementary phases were carried out: (i) the analysis of the inscriptions on the jars, along with the survey on historical medical texts, allowing for the positive identification of the plant ingredients of the remedies and their ancient use as medicines; (ii) the bibliographic research in modern pharmacological literature in order to validate or refute the historical uses; (iii) the realization of the checklist of plants potentially present in cultivation at the ancient Garden, concurrently with the comparison with the results of a previous in situ archaeobotanical study concerning pollen grains. For the species selection, considerations were made also regarding drug amounts in the remedies and pedoclimatic conditions of the study area. Out of the 150 vases, 108 contained plant-based remedies, corresponding to 148 taxa. The remedies mainly treated gastrointestinal and respiratory disorders. At least one of the medicinal uses was validated in scientific literature for 112 out of the 148 examined species. Finally, a checklist of 40 taxa, presumably hosted in the Hortus simplicium, was assembled.

Findings of Russian literature on the clinical application of Eleutherococcus senticosus (Rupr. & Maxim.): A narrative review.

ETHNOPHARMACOLOGICAL RELEVANCE: Eleutherococcus senticosus (Rupr. et Maxim.) Maxim (ES) (syn. Acanthopanax senticosus (Rupr. & Maxim.) Harms) is a medicinal plant used in traditional medicine of Russian Far East and East Asia and known as an adaptogen - a category of herbal medicinal products which have non-specific inter-system anti-stress effects throughout the human body. ES was first established as a medicinal plant officially in the pharmacopeia of the Union of Soviet Socialist Republics (USSR) in 1962, and is currently recommended by the European Medicines Agency (EMA) to be prescribed to treat symptoms of asthenia such as fatigue and weakness. AIM OF THE REVIEW: During the time of the USSR, a distinct research directive was undertaken on ES to examine substances which improve stamina and endurance, with over 1000 studies published. Due to security measures within the former USSR these papers were not accessible to the public and were never translated into English. This is the first study to make findings of the USSR studies on ES available to the international research and scientific community. METHODS: This study was an archival retrieval. References for studies were sought from printed journal and conference preceding's publications, then located within library catalogues of three libraries in St Petersburg Russia. Eligibility criteria included human clinical trials examining the efficacy of ES in any condition, published in the Russian language in the Soviet Union. RESULTS: A total of 46 studies published between 1962 and 1986 in the USSR were sourced. Of the retrieved articles, 29 were reported as placebo-controlled trials, 11 were reported as controlled trials and six studies did not report the study design. Trends in studies were those reporting on healthy volunteers (n=21) at a dose of 2 ml extract/day (n=14) examining outcomes such as physical and mental stamina under varying conditions, normal work conditions, high temperatures and high altitudes, incidence or prophylaxis of colds and influenza (n=5), effects on color perception and vision (n=2), work capacity (n=1), cognitive effects (n=1), prophylaxis of hearing loss (n=3), effects on blood cell counts (n=2) and sensitivity to UV radiation (n=1). CONCLUSIONS: ES appears to exhibit benefits for cognitive function and physical and mental endurance and its effect as a respiratory system infection prophylaxis treatment are promising. This study is the first to publish the findings of clinical trials on ES from the USSR, which supports the traditional use and offers a valuable contribution to the body of evidence on medicinal uses of ES when the data is applied within the context of its limitations.

Fenugreek Cultivation with Emphasis on Historical Aspects and its uses in Traditional Medicine and Modern Pharmaceutical Science.

Fenugreek (Trigonella foenum-graecum L.) is a native plant found in the parts of Iran to the North of India, and is presently planted also in other regions of the world. Fenugreek is considered a notable multipurpose medicinal and traditional herb in Iran, India, and China for several centuries. The most important components of fenugreek seeds are protein, neutral detergent fiber, gum, lipids, moisture, ash and starch. Fenugreek seeds and leaves are anti-cholesterolemic, anti-tumor, antiinflammatory, carminative, demulcent, deobstruent, emollient, expectorant, galactogogue, febrifuge, laxative, hypoglycaemic, restorative, parasiticide and uterine tonic and useful in burning sensation. Traditionally, fenugreek seeds being used worldwide are beneficial for bone and muscles, respiratory system, gastro-intestinal system, female reproductive system, cardio-vascular system, endocrinology and hepatic. Fenugreek helps reduce cholesterol, reduce cardiovascular risk, control diabetes, a good consolation for sore throats, a remedy for acid reflux, constipation, colon cancer prevention, appropriate for kidney trouble, skin infection, increase milk production, reduce menstrual discomfort, and reduce menopause symptoms. It is also an appetite suppressant that helps in weight loss. Both modern science and traditional medicine integration with novel technologies and discoveries will secure the cultivation of medicinal herbs and promote sustainability in the long-term and a wide-range.

'Psychosis of civilization': a colonial-situated diagnosis.

In the late 1930s, when colonial psychiatry was well established in the Maghreb, the diagnosis 'psychosis of civilization' appeared in some psychiatrists' writings. Through the clinical case of a Libyan woman treated by the Italian psychiatrist Angelo Bravi in Tripoli, this article explores its emergence and its specificity in a differential approach, and highlights its main characteristics. The term applied to subjects poised between two worlds: incapable of becoming 'like' Europeans - a goal to which they seem to aspire - but too far from their 'ancestral habits' to revert for a quiet life. The visits of these subjects to colonial psychiatric institutions, provided valuable new material for psychiatrists: to see how colonization impacted inner life and to raise awareness of the long-term socio-political dangers.

Geopolitics of bitterness: Deciphering the history and cultural biogeography of Quassia amara L.

ETHNOPHARMACOLOGICAL RELEVANCE: Quassia amara L. recently came into the spotlight in French Guiana, when it became the object of a biopiracy claim. Due to the numerous use records throughout the Guiana shield, at least since the 18th century, a thorough investigation of its origin seemed relevant and timely. In the light of the Convention on Biological Diversity (CBD) and the Nagoya protocol, questions about the origin of local knowledge are important to debate. AIM OF THE STUDY: Defining cultural biogeography as the dynamics through space and time of biocultural complexes, we used this theoretical framework to shed light on the complex biogeographical and cultural history of Q. amara. We explored in particular the possible transfer of medicinal knowledge on an Old World species to a botanically related New World one by enslaved Africans in Suriname. MATERIALS AND METHODS: Historical and contemporary literature research was performed by means of digitized manuscripts, archives and databases from the 17th to the 21st century. We retrieved data from digitized herbarium vouchers in herbaria of the Botanic Garden Meise (Belgium); Naturalis Biodiversity Center (the Netherlands); Missouri Botanical Garden, the Smithsonian National Museum of Natural History, the Field Museum (USA); Royal Botanic Gardens Kew (UK); the IRD Herbarium, French Guiana and the Museum National d'Histoire Naturelle (France). Vernacular names were retrieved from literature and herbarium specimens and compared to verify the origin of Quassia amara and its uses. RESULTS: Our exploration of digitized herbarium vouchers resulted in 1287 records, of which 661 were Q. amara and 636 were Q. africana. We observed that the destiny of this species, over at least 300 years, interweaves politics, economy, culture and medicine in a very complex way. Quassia amara's uses are difficult to attribute to specific cultural groups: the species is widely distributed in Central and South America, where it is popular among many ethnic groups. The species spread from Central to South America during the early 18th century due to political and economic reasons. This migration possibly resulted from simultaneous migration by religious orders (Jesuits) from Central America to northern South America and by Carib-speaking Amerindians (from northern South America to Suriname). Subsequently, through colonial trade networks, Q. amara spread to the rest of the world. The absence of African-derived local names in the Guiana shield suggests that Q. africana was not sufficiently familiar to enslaved Africans in the region that they preserved its names and transferred the associated medicinal knowledge to Q. amara. CONCLUSIONS: Cultural biogeography has proven an interesting concept to reconstruct the dynamics of biocultural interactions through space and time, while herbarium databases have shown to be useful to decipher evolution of local plant knowledge. Tracing the origin of a knowledge is nevertheless a complex adventure that deserves time and interdisciplinary studies.

The name to remember: Flexibility and contextuality of preliterate folk plant categorization from the 1830s, in Pernau, Livonia, historical region on the eastern coast of the Baltic Sea.

ETHNOPHARMACOLOGICAL RELEVANCE: Research on the folk categorization of nature in preliterate societies in Europe is complicated due to the fragmentation of the information available and is rarely undertaken. Yet the data is valuable and may provide, in certain circumstances, important insights, if not into novel medicines, then into the historical logic of selection and memorisation of plants useful from a medicinal perspective. AIMS OF THE STUDY: We aim to understand the ethnobotany of a preliterate society by analysing the emic (derived from people) perspective on nature-related culture of one of Europe's smaller nations, whose written language and culture was shaped in the 18th-19th centuries by other, larger nations of Europe, and thus from the etic (academic) perspective. We attempt to identify how folk categorization is reflected in the relationships between plant names and uses and to map the structure of those relationships. DATA AND METHODS: We base our analysis on one of the oldest ethnobotanical manuscripts and herbaria of the Baltic governorates, compiled in 1831 by an amateur botanist, Baltic German Pastor Johann Heinrich Rosenplänter (1782-1846), which was derived from conversations with his parishioners from the tiny Pärnu parish. The historical dataset was critically analysed from an ethnobotanical perspective in light of recent identifications of the herbarium specimens. RESULTS: Although the Rosenplänter collection is fragmentary, the logic of plant categorization by non-literate peasants at that time is clearly seen in the data. Plants preserved in the herbarium were predominantly used for ethno-medicinal, food or ethno-veterinary purposes, such as treating chronic skin and joint diseases as well as severe acute diseases in humans and animals. Among 129 folk taxa analysed, more than one third had apparent purpose-related plant names providing clear links to their use, whereas a few multifunctional plants had several names reflecting diverse uses. For example, Hypericum spp., which was used in three different ways, had three semantically distinct names. However, among the plants that Rosenplänter collected, there were also some that were simply named and described by people but lacked any usability data (e.g., Trollius europaeus), meaning that use as such was not the primary criterion for recognising a plant. The web-like structure of preliterate thinking in plant-related knowledge reveals a deep relationship with the environment and the interpretation of new elements through familiar natural objects. CONCLUSION: Our findings demonstrate that historical ethnobotanical data, if thoughtfully analysed, can be used not only for comparative purposes, but also for understanding the logic of preliterate thinking. We encourage future in-depth studies of historical ethnobotanical data in Europe in order to understand the relationship between nature and culture of native European populations.

De curandis hominum morbis: An 18th century medical prescription for measles and smallpox in the Nuevo Reino de Granada / De curandis hominum morbis: una receta médica del siglo XVIII para el sarampión y las viruelas en el Nuevo Reino de Granada

A collection of more than one hundred medical recipes from the late 18th century was donated by Presbyter Cipriano Rodríguez Santa María, institutional eponym of the collection at the Historical Archive "Octavio Arizmendi Posada" of the library of the Universidad de La Sabana in Colombia. These texts represent an important historical and medical legacy and they constitute an important basis for understanding the colonial and traditional therapeutics related to various diseases. In this article, we describe one of these recipes for the treatment of smallpox and measles as a contribution to the history of medicine in Colombia.

En el Archivo Histórico de la Biblioteca "Octavio Arizmendi Posada" de la Universidad de La Sabana, se encuentra una colección de más de un centenar de recetas médicas de finales del siglo XVIII donadas por el presbítero Cipriano Rodríguez Santa María, epónimo institucional del archivo. Estos textos son un legado histórico médico y un fundamento para comprender la terapéutica colonial y tradicional de diversas enfermedades. En este artículo, se describen algunas recetas para el tratamiento de la viruela y el sarampión, como aporte a la historia de la medicina en Colombia.

Investigaciones clínicas sobre Medicina Natural y Tradicional publicadas en revistas cubanas / Clinical researches on natural and traditional medicine published in Cuban journals

RESUMEN Introducción: los profesionales dedicados a la medicina natural y tradicional deben establecer y divulgar las evidencias científicas para su uso adecuado y seguro. Objetivos: identificar artículos científicos relacionados con investigaciones clínicas sobre medicina natural y tradicional en revistas médicas cubanas y describir algunas de sus características. Material y Método: estudio descriptivo, transversal; se analizaron los artículos originales publicados entre los años 2007 y 2018 en seis revistas médicas cubanas: Plantas Medicinales, Medicina Natural y Tradicional, Medicina General Integral, Estomatología, Medicina Militar y Farmacia; realizados en personas y en Cuba. Se identificó año de publicación, tipo de estudio (descriptivo, analítico, ensayo clínico), variable principal (eficacia, seguridad, otros), provincia dónde se ejecutó; en los ensayos clínicos se identificó la modalidad empleada, la enfermedad del paciente y el nivel de atención de salud en que se realizaron. Resultados: se encontraron 36 artículos; se publicaron más en los años 2007 y 2016; 69,4 % eran ensayos clínicos; la mayoría se realizó en La Habana (41,6%). En los ensayos clínicos las modalidades más estudiadas fueron la acupuntura (28,0 %) y la fitoterapia, 20,0%; se emplearon más en pacientes con enfermedades estomatológicas, 28,0%; su ejecución predominó en el nivel primario de atención de salud, 64,0%. Conclusiones: fueron insuficientes los artículos relacionados con investigaciones clínicas sobre medicina natural y tradicional que se publicaron en seis revistas que abordan esta temática, esta situación atenta contra la prescripción de esta opción terapéutica, basada en evidencias científicas (AU).

SUMMARY Introduction: the professionals devoted to natural and traditional medicine should study and publish the scientific evidences for its rational and safe use. Objectives: to identify scientific articles related to clinical researches on natural and traditional medicine in Cuban medical journals and to describe some of their characteristics. Materials and methods: a cross-sectional descriptive study; the authors analyzed the original articles published in the period 2007-2018 on researches made in Cuban people and in Cuba in six Cuban medical journals: Plantas Medicinales, Medicina Natural y Tradicional, Medicina General Integral, Estomatología, Medicina Militar y Farmacia. The year of publication, kind of study (descriptive, analytic, clinical trial), main variable (efficacy, safeness, others), and province where they were identified; in the case of clinical trial: the used modality, the patient's disease and the level of the health care where they took place were also identified. Results: 36 articles were found; the years when they were published the most were 2007 and 2016; 69.4 % were clinical trials; most of them were carried out in La Habana (41.6 %). In clinical trials, the most studied modalities were acupuncture (28.0 %) and physiotherapy (20.0 %); they were used more in patients with dental diseases (28.0 %); they were used mainly at the primary health care (64.0 %). Conclusions: there were insufficient the articles related to clinical researches on natural and traditional medicine published in six journals approaching these themes; this situation attempts against the use of this therapeutic use, based on scientific evidences (AU).